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Related Experiment Video

Updated: May 29, 2026

Live Imaging of Cell Extrusion from the Epidermis of Developing Zebrafish
09:39

Live Imaging of Cell Extrusion from the Epidermis of Developing Zebrafish

Published on: June 27, 2011

Development of zebrafish epidermis.

Wei-Jen Chang1, Pung-Pung Hwang

  • 1Institute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taiwan.

Birth Defects Research. Part C, Embryo Today : Reviews
|September 21, 2011
PubMed
Summary

Zebrafish epidermal ionocytes, similar to kidney cells, help regulate stress acclimation via cell differentiation. Their homologies offer a model for studying mammalian cell development and function.

Area of Science:

  • Comparative physiology
  • Developmental biology
  • Cell biology

Background:

  • Zebrafish epidermal ionocytes share functional and expressional similarities with mammalian kidney cells.
  • Understanding ionocyte development is crucial for comparative studies.

Purpose of the Study:

  • To review zebrafish epidermis development and stress acclimation mechanisms.
  • To highlight cellular homologies between zebrafish ionocytes and mammalian kidney cells.
  • To establish the zebrafish epidermis as a model for mammalian cell research.

Main Methods:

  • Literature review of current findings on zebrafish epidermis development.
  • Analysis of stress acclimation pathways involving cell differentiation.
  • Comparative analysis of ionocyte and kidney cell characteristics.

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Zebrafish Keratocyte Explants to Study Collective Cell Migration and Reepithelialization in Cutaneous Wound Healing
09:35

Zebrafish Keratocyte Explants to Study Collective Cell Migration and Reepithelialization in Cutaneous Wound Healing

Published on: February 25, 2015

Live Imaging of Innate Immune and Preneoplastic Cell Interactions Using an Inducible Gal4/UAS Expression System in Larval Zebrafish Skin
08:52

Live Imaging of Innate Immune and Preneoplastic Cell Interactions Using an Inducible Gal4/UAS Expression System in Larval Zebrafish Skin

Published on: February 3, 2015

Related Experiment Videos

Last Updated: May 29, 2026

Live Imaging of Cell Extrusion from the Epidermis of Developing Zebrafish
09:39

Live Imaging of Cell Extrusion from the Epidermis of Developing Zebrafish

Published on: June 27, 2011

Zebrafish Keratocyte Explants to Study Collective Cell Migration and Reepithelialization in Cutaneous Wound Healing
09:35

Zebrafish Keratocyte Explants to Study Collective Cell Migration and Reepithelialization in Cutaneous Wound Healing

Published on: February 25, 2015

Live Imaging of Innate Immune and Preneoplastic Cell Interactions Using an Inducible Gal4/UAS Expression System in Larval Zebrafish Skin
08:52

Live Imaging of Innate Immune and Preneoplastic Cell Interactions Using an Inducible Gal4/UAS Expression System in Larval Zebrafish Skin

Published on: February 3, 2015

Main Results:

  • Zebrafish epidermis development involves regulated cell differentiation.
  • Stress acclimation is mediated by the induction of specific cell differentiation pathways.
  • Significant cellular homologies exist between zebrafish epidermal ionocytes and mammalian kidney cells.

Conclusions:

  • Zebrafish epidermal ionocytes are a valuable model for studying mammalian kidney cell development and function.
  • The zebrafish epidermis provides insights into stress response and cell differentiation mechanisms.
  • Further research can leverage the zebrafish model for in vivo studies of mammalian cell biology.