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Updated: May 29, 2026
06:23
Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo
Published on: August 4, 2018
[Continuous blood coagulation in chronic opisthorchiasis]
Meditsinskaia Parazitologiia I Parazitarnye Bolezni
|September 22, 2011
Summary
Chronic Opisthorchis invasion accelerates blood coagulation and activates platelets in animal models. This parasitic infection, opisthorchiasis, consistently leads to lower fibrinogen levels, impacting blood clotting.
Area of Science:
- Parasitology
- Hematology
- Immunology
Context:
- Chronic Opisthorchis invasion is a significant health concern.
- Understanding the hemostatic changes associated with opisthorchiasis is crucial.
Purpose:
- To investigate the effects of chronic Opisthorchis invasion on blood coagulation and hemostasis.
- To determine the relationship between infection severity and hemostatic alterations.
Summary:
- Animal studies reveal that chronic Opisthorchis invasion accelerates blood coagulation.
- This invasion induces hypercoagulation and platelet activation.
- Hypofibrinogenemia is a consistent finding in chronic opisthorchiasis, regardless of invasion intensity.
Impact:
- Findings highlight the prothrombotic state induced by Opisthorchis.
- This research contributes to understanding the pathophysiology of opisthorchiasis.
- Potential implications for managing bleeding risks in infected individuals.
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