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Updated: May 29, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

Transcatheter aortic valve replacement: the changing paradigm of aortic stenosis treatment

David Liff1, Vasilis Babaliaros, Peter Block

  • 1Emory University Hospital, 1364 Clifton Rd., Atlanta, GA 30322, USA.

Expert Review of Cardiovascular Therapy
|September 22, 2011
PubMed

Insights

Transcatheter aortic valve replacement (TAVR) offers an effective treatment for severe aortic stenosis in high-risk surgical patients. This minimally invasive procedure shows improved safety and efficacy, though patient selection remains crucial.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Aortic stenosis is a prevalent valvular heart disease, frequently necessitating surgical intervention.
  • Surgical aortic valve replacement (SAVR) is the established treatment, but comorbidities and age limit surgical eligibility for many patients.
  • Transcatheter aortic valve replacement (TAVR) has emerged as a vital alternative for high-risk surgical candidates.

Purpose of the Study:

  • To evaluate the safety and efficacy of TAVR as a therapeutic option for patients with severe aortic stenosis.
  • To compare TAVR outcomes with existing medical therapy in inoperable patients.
  • To identify optimal patient selection criteria for TAVR.

Main Methods:

  • Review of clinical data and outcomes for patients undergoing TAVR.
  • Comparison of TAVR efficacy against medical management in specific patient cohorts.
  • Analysis of device innovations and procedural experience influencing TAVR outcomes.

Main Results:

  • TAVR demonstrates improved safety and efficacy due to technological advancements and procedural experience.
  • TAVR is superior to medical therapy for inoperable patients with severe aortic stenosis.
  • Ongoing research focuses on refining patient selection for TAVR.

Conclusions:

  • TAVR represents a significant advancement in managing severe aortic stenosis, particularly for high-risk individuals.
  • Further research is needed to delineate the precise indications and long-term outcomes for TAVR across diverse patient populations.

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