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Updated: May 29, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Cardiac resynchronization therapy in mildly symptomatic heart failure: the earlier the better

Sean Balmain1, Michael A McDonald

  • 1Division of Cardiology, University Health Network and Mount Sinai Hospital, University of Toronto, 600 University Avenue, Mount Sinai Hospital, Toronto, Ontario, Canada.

Expert Review of Cardiovascular Therapy
|September 22, 2011
PubMed

Insights

Cardiac resynchronization therapy (CRT) is an effective treatment for heart failure patients, now showing promise even in mild cases. Expanding CRT indications offers new hope for improving patient outcomes across the heart failure spectrum.

Area of Science:

  • Cardiology
  • Medical Technology

Background:

  • Cardiac resynchronization therapy (CRT) is an established treatment for moderate-to-severe heart failure.
  • CRT improves mortality and functional capacity in patients with left ventricular systolic impairment and prolonged QRS duration.

Purpose of the Study:

  • To explore the expanding indications for CRT in heart failure treatment.
  • To assess the potential of pacemaker technology across the heart failure continuum.

Main Methods:

  • Review of recent evidence on CRT efficacy.
  • Analysis of patient outcomes in mild heart failure.

Main Results:

  • Recent evidence supports CRT as effective for mild heart failure.
  • CRT indications are expanding, offering potential benefits across the heart failure spectrum.

Conclusions:

  • CRT is increasingly recognized for its efficacy beyond moderate-to-severe heart failure.
  • Future applications of CRT require careful consideration of healthcare resource limitations.

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