Related Experiment Video
Updated: May 29, 2026

An Iodide-Yellow Fluorescent Protein-Gap Junction-Intercellular Communication Assay
Published on: February 1, 2019
Connexins in epidermal homeostasis and skin disease
Claire A Scott1, Daniel Tattersall, Edel A O'Toole
1Queen Mary University of London, London, UK.
Abstract:
The expression of multiple connexin (Cx) types in the epidermis, their differential expression during wound closure and the association of skin pathology with specific Cx gene mutations, are indicative of important functions for Cxs in the skin. In this review, we focus on the role of Cx proteins in the epidermis and during wound healing and discuss mutations in Cx genes which cause skin disease. This article is part of a Special Issue entitled: The Communicating junctions, composition, structure and characteristics.
Related Concept Videos
Renewal of Skin Epidermal Stem Cells
Gap Junctions
Gap Junctions
Desmosomes
Clinical Applications of Epidermal Stem Cells
Sensory Functions of the Skin
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
