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[Late-onset diabetes 1989].

¹Endokrinologische Abteilung, Inselspital Bern.

Schweizerische Medizinische Wochenschrift

|June 2, 1990

Summary

This summary is machine-generated.

Type II diabetes, common in older adults, involves insulin resistance and secretion issues. Management includes diet, medication, and monitoring HbA1c for better blood sugar control.

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Area of Science:

Endocrinology
Geriatrics
Metabolic Diseases

Background:

Type II diabetes is prevalent in older populations, affecting approximately 7% of 60-year-olds in the US.
Genetic factors significantly contribute to the development of type II diabetes.
Metabolic disturbances stem from insulin resistance and impaired insulin secretion.

Purpose of the Study:

To outline the etiology, pathophysiology, and management of type II diabetes.
To discuss the complications and recent treatment advancements for type II diabetes.

Main Methods:

Review of existing literature on type II diabetes.
Analysis of treatment strategies including diet, oral antidiabetics, and insulin therapy.
Discussion of diagnostic markers like C-peptide and HbA1c.

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Main Results:

Type II diabetes is linked to a twofold increase in age-specific mortality, primarily due to macrovascular complications.
Dietary modifications (increased carbohydrates and fiber, decreased fat) are foundational.
Monitoring C-peptide and HbA1c aids in treatment decisions and assessment.

Conclusions:

Effective management of type II diabetes involves a multi-faceted approach including lifestyle changes and pharmacological interventions.
Significant progress has been made in treating chronic complications, particularly diabetic retinopathy.
Continued research is needed to further understand and manage postreceptor defects in insulin resistance.