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Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions01:15

Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions

PK–PD modeling has significantly influenced FDA regulatory decisions, particularly drug approval, dosage optimization, and labeling. These models integrate pharmacokinetics (PK) and pharmacodynamics (PD) to predict drug behavior and effects, aiding in optimizing dosing regimens and enhancing the probability of clinical trial success.One notable example is Nesiritide (Natrecor®), a recombinant human brain natriuretic peptide for treating acute decompensated congestive heart failure (CHF).

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Related Experiment Videos

Medication therapy management in the primary care setting: a pharmacist-based pay-for-performance project.

Carrie Foust Koenigsfeld1, Kristin K Horning, Craig D Logemann

  • 1Department of Clinical Sciences, Drake College of Pharmacy and Health Sciences, University Avenue, Des Moines, IA 50311, USA. carrie.koenigsfeld@drake.edu

Journal of Pharmacy Practice
|September 22, 2011
PubMed
Summary

Medication therapy management improved chronic disease control and generic drug use in clinics. Pharmacist involvement in patient care enhances outcomes and reduces medication costs.

Related Experiment Videos

Area of Science:

  • Clinical Pharmacy
  • Pharmacoeconomics
  • Chronic Disease Management

Background:

  • Chronic diseases like diabetes, hyperlipidemia, hypertension, and asthma require ongoing management.
  • Medication therapy management (MTM) services aim to optimize drug therapy and improve patient outcomes.
  • Generic drug prescribing can lead to significant cost savings in healthcare.

Purpose of the Study:

  • To evaluate the impact of MTM services on chronic disease management.
  • To assess the effect of MTM on generic drug prescribing rates.
  • To determine the effectiveness of clinic-based pharmacist interventions.

Main Methods:

  • A Pay-for-Performance (PFP) project involved clinic-based pharmacists in Iowa and South Dakota.
  • Pharmacists managed approximately 300 patients with at least one of four chronic conditions.
  • Outcomes measured included achievement of disease-specific goals and generic prescribing rates for key drug classes.

Main Results:

  • A high percentage of patients achieved treatment goals for diabetes, hypertension, hyperlipidemia, and asthma.
  • 88.8% of patients received at least one medication review.
  • Generic prescribing rates for evaluated medications ranged from 65.8% to 79.4%.

Conclusions:

  • Clinics utilizing clinical pharmacist services demonstrated high patient goal achievement rates.
  • MTM services positively impact chronic disease management.
  • A multidisciplinary approach involving pharmacists can improve patient care and reduce medication costs.