Related Experiment Video
Updated: May 29, 2026
Orienteering as a Tool for Cognitive Research: An Implementation Guide
Published on: November 29, 2024
Increased basal plasma brain-derived neurotrophic factor levels in sprint runners
Paulo Roberto Correia1, Fulvio Alexandre Scorza, Sérgio Gomes da Silva
1Department of Physiology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
Objective:
Exercise is known to enhance circulating brain-derived neurotrophic factor (BDNF) levels in healthy humans. BDNF changes have been measured in endurance but not in strength exercise. The present study aimed to investigate whether anaerobic activity such as sprinting differentially alters basal plasma BDNF concentration.
Methods:
Brazilian sprinters (100 m) at either the international (Olympics and Outdoor World Championships) (n = 14) or the domestic level (n = 8), and sedentary subjects (n = 15), were recruited. Plasma BDNF concentrations were analyzed by enzyme-linked immunosorbent assay.
Results:
The basal plasma BDNF concentrations were significantly higher in the international and the domestic sprinters than in the sedentary subjects. In addition, sprinters at the international level had higher plasma BDNF concentrations than those at the domestic level.
Conclusion:
Our findings suggest that increased basal plasma BDNF level is related to enhanced exercise performance.
