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Updated: May 29, 2026

Characterizing the Composition of Molecular Motors on Moving Axonal Cargo Using "Cargo Mapping" Analysis
Published on: October 30, 2014
Co-operative transport by molecular motors
Florian Berger1, Corina Keller, Melanie J I Müller
1Max Planck Institute of Colloids and Interfaces, 14424 Potsdam, Germany. florian.berger@mpikg.mpg.de
Abstract:
Intracellular transport is often driven co-operatively by several molecular motors, which may belong to one or several motor species. Understanding how these motors interact and what co-ordinates and regulates their movements is a central problem in studies of intracellular transport. A general theoretical framework for the analysis of such transport processes is described, which enables us to explain the behaviour of intracellular cargos by the transport properties of individual motors and their interactions. We review recent advances in the theoretical description of motor co-operativity and discuss related experimental results.
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