Redox signalling via the cellular thiolstat.

Claus Jacob1

  • 1Division of Bioorganic Chemistry, School of Pharmacy, Saarland University, Campus, D-66123 Saarbrücken, Germany. c.jacob@mx.uni-saarland.de

Summary

Cells use a complex network of cysteine-containing proteins to regulate internal redox balance, known as the thiolstat. Understanding this system is key for future drug development targeting cellular defense and survival.

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