Related Experiment Video
Updated: May 29, 2026
Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
Published on: July 28, 2013
Microstructural disruption of white matter in heroin addicts revealed by diffusion tensor imaging: a controlled study
Xuyi Wang1, Xuhui Zhou, Yanhui Liao
1Central South University, Changsha 410011, China.
Objective:
To examine white matter integrity in heroin-dependent patients and matched normal controls with diffusion tensor imaging (DTI).
Methods:
The fractional anisotropy was compared between 15 heroin-dependent patients and 15 controls.
Results:
We found the fractional anisotropy was significantly decreased in specific brain regions of the heroin-dependent patients (P<0.001 uncorrected), including the frontal gyrus, the parietal lobule, the insula, and the corpus callosum.
Conclusion:
The presence of microstructural abnormality is found in the white matter of several brain regions of heroin-dependent patients.
