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Updated: May 29, 2026

Sample Preparation in Quartz Crystal Microbalance Measurements of Protein Adsorption and Polymer Mechanics
Published on: January 22, 2020
Hearing what you cannot see and visualizing what you hear: interpreting quartz crystal microbalance data from
Ilya Reviakine1, Diethelm Johannsmann, Ralf P Richter
1Biosurfaces Unit, CIC biomaGUNE, Paseo Miramon 182, 20009 Donostia-San Sebastian, Spain. ireviakine@cicbiomagune.es
Abstract:
Over the last 2 decades, the quartz crystal microbalance (QCM or QCM-D) has emerged as a versatile tool for investigating soft and solvated interfaces between solid surfaces and bulk liquids because it can provide a wealth of information about key structural and functional parameters of these interfaces. In this Feature, we offer QCM users a set of guidelines for interpretation and quantitative analysis of QCM data based on a synthesis of well-established concepts rooted in rheological research of the last century and of new results obtained in the last several years.
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