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Updated: May 29, 2026

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
Published on: February 10, 2023
Low genetic diversity of Pneumocystis jirovecii among Cuban population based on two-locus mitochondrial typing
Yaxsier de Armas1, Vicente Friaza, Virginia Capó
1Institute of Tropical Medicine Pedro Kourí, Havana, Cuba.
Abstract:
Genotypes of two different loci of the Pneumocystis jirovecii mitochondrial gene were studied in specimens from a total of 75 Pneumocystis pneumonia patients in Spain, France and Cuba. A new genotype of the mitochondrial small subunit rRNA gene of P. jirovecii (160A/196T) was identified, which was revealed to be the most common in these three countries, especially in Cuba where its proportion reached 93.8%. Our data imply that the new genotype might be circulating worldwide and also suggests that the distribution of P. jirovecii genotypes could be narrower in islands such as Cuba.
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