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Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Goiter01:27

Goiter

Goiter refers to an abnormal enlargement of the thyroid gland that may appear as a diffuse goiter (uniform enlargement) or nodular (single or multiple nodules). Functionally, it is classified as nontoxic (normal/low hormone levels) or toxic (excess hormone production).PathophysiologyDiffuse thyroid enlargement typically results from prolonged stimulation by thyroid-stimulating hormone (TSH) or TSH-like agents, commonly seen in hypothyroidism or iodine deficiency. In contrast, in hyperthyroid...
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Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
The Thyroid Gland01:23

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions
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Postmortem changes of the thyroid on computed tomography.

Masanori Ishida1, Wataru Gonoi, Kazuchika Hagiwara

  • 1Department of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan. masanoriishida@hotmail.com

Legal Medicine (Tokyo, Japan)
|September 24, 2011
PubMed
Summary

Postmortem computed tomography (PMCT) reveals a decrease in thyroid computed tomography (CT) values after death. This finding was consistent regardless of the time elapsed since antemortem CT imaging.

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Area of Science:

  • Forensic Radiology
  • Medical Imaging
  • Pathology

Background:

  • Postmortem computed tomography (PMCT) is an increasingly valuable tool in forensic investigations.
  • Understanding postmortem changes in organ tissues is crucial for accurate interpretation of PMCT findings.

Purpose of the Study:

  • To evaluate the radiographic features of the thyroid gland using PMCT.
  • To compare antemortem computed tomography (AMCT) and PMCT findings of the thyroid.
  • To assess changes in thyroid CT values postmortem.

Main Methods:

  • A study involving 32 subjects who underwent both AMCT and PMCT prior to conventional autopsy.
  • Statistical analysis to compare thyroid CT values between AMCT and PMCT.
  • Correlation analysis to determine the relationship between time since AMCT and CT value differences.

Main Results:

  • Thyroid CT values showed a statistically significant decrease after death (114.2 Hounsfield Units on AMCT vs. 107.7 HU on PMCT, P=0.023).
  • No significant correlation was found between the time elapsed since AMCT and the observed changes in thyroid CT values (P>0.05).

Conclusions:

  • Thyroid CT values decrease following death.
  • These changes are observable via PMCT and are not significantly influenced by the post-AMCT interval.