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Depressive symptomatology in children and adolescents with chronic renal insufficiency undergoing chronic dialysis

Edith G Hernandez1, Reyner Loza, Horacio Vargas

  • 1Pediatric Nephrology Unit, Cayetano Heredia National Hospital, San Martín de Porras, Lima, Lima 31, Peru.

International Journal of Nephrology
|September 24, 2011
PubMed

Insights

Depressive symptoms are common in children with chronic renal insufficiency (CRI), particularly in females undergoing chronic peritoneal dialysis (CPD). Lower dialysis efficiency was linked to increased depressive symptomatology.

Area of Science:

  • Pediatric Nephrology
  • Child and Adolescent Psychiatry
  • Renal Replacement Therapy

Background:

  • Chronic renal insufficiency (CRI) significantly impacts children's quality of life.
  • Mental health, specifically depressive symptomatology, is a critical concern in pediatric patients with CRI.
  • Dialysis modalities, hemodialysis (HD) and chronic peritoneal dialysis (CPD), may influence psychological well-being.

Purpose of the Study:

  • To determine the frequency of depressive symptomatology in children and adolescents with CRI undergoing HD and CPD.
  • To identify factors associated with depressive symptomatology in this patient population.

Main Methods:

  • A descriptive study utilizing the Birleson Scale to assess depressive symptomatology.
  • Inclusion of 67 pediatric patients with CRI (mean age 14.76 ± 2.71 years).
  • Comparison of depressive symptoms between patients undergoing HD and CPD, and analysis of associated clinical parameters.

Main Results:

  • 43.28% of patients exhibited low occurrence and 10.45% high occurrence of depressive symptomatology.
  • All patients with high depressive symptomatology were female (P = 0.04) and lacked a confidant (P = 0.03).
  • Lower weekly K(t)/V was associated with depressive symptomatology in CPD patients (P = 0.01).

Conclusions:

  • Depressive symptomatology is prevalent in pediatric CRI patients, with a higher occurrence in females.
  • Social support and dialysis adequacy (K(t)/V) are potential factors influencing mental health in these patients.
  • Further research is warranted to explore interventions for managing depressive symptoms in pediatric CRI.

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