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Updated: May 29, 2026

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
[Sphincter-saving resection for low rectal cancer]
Norio Saito1, Masaaki Ito, Akihiro Kobayashi
1Colorectal Surgery Division, Department of Surgical Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Rectal cancer surgery aims for R0 resection and sphincter preservation. Techniques like ultra-low anterior resection (U-LAR) and intersphincteric resection (ISR) help maintain anal function, reducing the need for abdominoperineal resection.
Area of Science:
- Surgical Oncology
- Gastrointestinal Surgery
- Colorectal Surgery
Context:
- Achieving R0 resection, anal sphincter preservation, and local control are paramount in rectal cancer surgery.
- Ultra-low anterior resection (U-LAR) is standard for lower rectal cancer, often using stapled anastomosis for reconstruction.
- Sphincter preservation techniques include pull-through operations, U-LAR, intersphincteric resection (ISR), and external sphincter resection (ESR).
Purpose:
- To review sphincter-preserving surgical techniques for rectal cancer.
- To discuss the role of U-LAR, ISR, and ESR in maintaining anal function.
- To highlight the need for clarity on long-term oncologic outcomes and anal function after these procedures.
Summary:
- U-LAR, ISR, and ESR are advanced surgical options for rectal cancer, aiming to preserve anal sphincter function.
- While these techniques can reduce abdominoperineal resection rates, long-term oncologic outcomes and functional results require further investigation.
- Careful patient selection based on tumor characteristics and patient preference is crucial for successful application.
Impact:
- These sphincter-preserving approaches can significantly decrease the rate of abdominoperineal resection in very low rectal cancers.
- Improved understanding of long-term outcomes will refine surgical decision-making and patient counseling.
- Enhanced functional preservation contributes to a better quality of life for rectal cancer survivors.
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