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Updated: May 29, 2026
07:19
Generation and Culturing of High-Grade Serous Ovarian Cancer Patient-Derived Organoids
Published on: January 6, 2023
Primary ovarian non-Hodgkin's lymphoma
N Arnogiannaki1, C Grigoriadis, D Zygouris
1Department of Pathology, St. Savvas Anticancer-Oncologic Hospital, Athens, Greece.
European Journal of Gynaecological Oncology
|September 28, 2011
Summary
Primary ovarian non-Hodgkin's lymphoma (PONHL) is a rare condition. This case study shows successful treatment with chemotherapy, indicating PONHL has outcomes similar to other non-Hodgkin's lymphomas.
Area of Science:
- Oncology
- Hematology
- Gynecologic Oncology
Background:
- Primary ovarian non-Hodgkin's lymphoma (PONHL) is an exceptionally rare malignancy.
- Literature review and case presentation of PONHL.
Observation:
- A 24-year-old woman presented with abdominal pain.
- Diagnostic procedures included surgery (salpingo-oophorectomy, omentectomy, lymphadenectomy, appendectomy, curettage) and biopsies.
- Histopathology confirmed diffuse large B-cell non-Hodgkin's lymphoma of the ovary.
Findings:
- The patient received postoperative chemotherapy.
- The patient achieved remission and remained disease-free for 15 months post-surgery.
Implications:
- PONHL management is based on treating it as a localized form of systemic disease.
- PONHL patient outcomes are comparable to those with other non-Hodgkin's lymphomas (NHL).
- Highlights the importance of timely diagnosis and multimodal treatment for rare gynecologic lymphomas.
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