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Antipsychotic-induced amenorrhea.

Mary V Seeman¹

¹Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. mary.seeman@utoronto.ca

Journal of Mental Health (Abingdon, England)

|September 28, 2011

Summary

Antipsychotic drug-induced amenorrhea can negatively impact women with schizophrenia, affecting contraception use and sense of femininity. Efforts should focus on preventing this significant side effect.

Area of Science:

Psychiatry
Women's Health
Reproductive Health

Background:

Antipsychotic medications for schizophrenia frequently cause amenorrhea.
The broader impact of this side effect remains under-researched.

Purpose of the Study:

To review the literature concerning the significance of menstruation for women.
To explore the meaning of menstruation across diverse cultures and for women with schizophrenia.

Main Methods:

A comprehensive literature review was conducted.
The review synthesized findings on the meanings of menstruation in general, cross-culturally, and specifically for women diagnosed with schizophrenia.

Main Results:

Menstruation holds ambivalent meanings for many women.

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Menstrual loss in women with schizophrenia can lead to issues like contraceptive failure, pseudocyesis, pregnancy denial, perceived early menopause, and diminished femininity.

Conclusions:

Preventing antipsychotic-induced amenorrhea is crucial.
Clinical strategies should aim to mitigate this adverse effect in women with schizophrenia.