Behavioral problems, cognitive difficulties and quality of life in children with epilepsy: an analysis of parental

Carmen Soria1, Sylvie Escolano, Sandra El Sabbagh

  • 1a Université Paris Descartes, Institut de Psychologie, Laboratoire de Psychologie et de Neuropyschologie Cognitives - CNRS FRE 3292 , Boulogne-Billancourt , France.

Insights

Proxy reports assess Quality of Life (QOL) and behavior in children with epilepsy. New tools are validated for all children, showing epilepsy type, age, and school setting impact QOL domains.

Area of Science:

  • Pediatric Neurology
  • Quality of Life Research
  • Epilepsy Management

Background:

  • Assessing Quality of Life (QOL) and behavior in children with epilepsy, especially those with cognitive impairments or young age, relies on proxy reports.
  • Existing QOL tools may not be universally applicable across diverse epilepsy types and comorbidities in pediatric populations.

Purpose of the Study:

  • To propose and validate proxy Quality of Life (QOL) tools suitable for all children with epilepsy, regardless of cognitive status.
  • To investigate the influence of epilepsy characteristics (syndrome, age of onset) and child-specific factors (age, school setting) on QOL.

Main Methods:

  • Adaptation of existing QOL scales and development of a new parental questionnaire for proxy assessment.
  • Inclusion of 219 children with varied epilepsy types, with and without cognitive impairment.
  • Analysis of QOL domains including global QOL, illness impact, emotional well-being, behavior, sociability, and parental QOL.

Main Results:

  • School situation, epilepsy syndrome, and child's age significantly impacted various QOL domains.
  • The developed proxy QOL tools demonstrated applicability across different pediatric epilepsy populations.
  • Epilepsy syndromes and associated factors were found to critically influence parental concerns and QOL.

Conclusions:

  • The proposed proxy QOL tools are effective for assessing children with epilepsy in clinical and research settings, irrespective of comorbidities.
  • Understanding the interplay between epilepsy characteristics, child's situation, and QOL is crucial for comprehensive pediatric epilepsy care.

Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Learning Disabilities01:25

Learning Disabilities

Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...