[Predictive value C-reactive protein assessment level in women with arterial hypertension]

Classic modifiable cardiovascular risk factors, such as blood pressure and dyslipidaemia are incorporated into clinical practice to estimate the 10-year risk of fatal cardiovascular disease (CVD): the SCORE project. To improve CVD risk estimation in women we compared predictive value of two models: risk chart based on the SCORE study and the Reynolds Risk Score in 134 women with hypertension to optimise risk stratification and preventive strategies in high-risk individuals. We concluded that Reynolds Risk model causes clinically relevant changes in risk category classification compared to risk chart SCORE and improves risk stratification. Addition of C-reactive protein to Reynolds Risk model improves it predictive value regardless of other risk factors. C-reactive protein is a strong marker of atherosclerosis, can be useful in women for risk stratification in daily practice regardless of risk prediction model.