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Updated: May 29, 2026

A Modified Method for Heterotopic Mouse Heart Transplantion
Published on: June 23, 2014
A successful 4S heart transplantation
Maha A Al-Mohaissen1, Andrew P Ignaszewski, Anson Cheung
1Division of Cardiology Adult Heart Transplant Program, St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Abstract:
Donor recipient matching is paramount to successful heart transplantation. The presence of allosensitization decreases the transplant candidate's donor pool, prolongs the time to transplantation, and increases the post-transplant mortality and morbidity. Various strategies are applied to reduce antibody loads with mixed results being reported. The development of a new listing criterion by the Canadian Cardiac Transplant Network (CCTN) for sensitized patients may overcome this problem by increasing the odds that a given recipient receives an organ from an appropriately matched donor. The success of this case gives hope to patients and provides insights into the treatment of sensitized patients.

