Related Experiment Video
Updated: May 29, 2026

06:23
Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Adjacent level disk disease--is it really a fusion disease?
1ORTON Orthopaedic Hospital, Helsinki, Finland. teija.lund@orton.fi
The Orthopedic Clinics of North America
|September 28, 2011
Summary
Adjacent segment degeneration (ASD) after spinal fusion is common. This review examines ASD causes, risks, and clinical impact, discussing motion-preserving technologies as a potential solution.
Area of Science:
- Spine surgery outcomes
- Biomechanical analysis
- Degenerative spine disease
Background:
- Adjacent segment degeneration (ASD) frequently occurs post-spinal fusion.
- The etiology of ASD, whether fusion-induced or due to patient predisposition, is debated.
Purpose of the Study:
- To review the biomechanical and clinical literature on ASD.
- To explore risk factors and clinical impact of ASD.
- To discuss motion-preserving technologies for adjacent segments.
Main Methods:
- Literature review of biomechanical and clinical studies.
- Analysis of existing research on spinal fusion and degeneration.
- Discussion of theoretical benefits of motion-preserving devices.
Main Results:
- ASD is a common complication following spinal fusion.
- Multiple risk factors contribute to ASD development.
- The clinical significance and progression of ASD are variable.
Conclusions:
- Further research is needed to fully elucidate ASD causes.
- Motion-preserving technologies offer a potential strategy to mitigate ASD.
- Understanding ASD is crucial for optimizing spinal fusion outcomes.
Related Concept Videos
Degenerative Disc Disease I: Introduction
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Structural Joints: Cartilaginous Joints
As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary or...
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary or...