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Updated: May 29, 2026
HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells
Published on: July 20, 2016
Carbonyl group serum levels are associated with CD38 expression in patients with B chronic lymphocytic leukemia
Caterina Musolino1, Alessandro Allegra, Andrea Alonci
1Division of Haematology, University of Messina, Messina, Italy.
Objectives:
To evaluate carbonyl groups (CG) serum levels in B-chronic lymphocytic leukemia (B-CLL) patients.
Design And Methods:
CG serum levels were assessed in 48 B-CLL patients and in 30 control subjects.
Results:
CG were increased in B-CLL patients. We found a positive correlation between CG with CD38 expression and a negative correlation with ZAP 70 expression.
Conclusions:
B-CLL patients displayed an unbalance of the oxidative stress. CG serum levels could be considered as a prognostic factor in B-CLL.
