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Related Concept Videos

Improving Translational Accuracy02:07

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
Improving Translational Accuracy02:07

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Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
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Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value.  Highly accurate measurements...
Accuracy and Precision01:52

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Accuracy, limits, and approximations are common in many fields, especially in engineering calculations. These concepts are imperative for ensuring that a given value is as close as possible to its true value.
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Related Experiment Video

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Movement Retraining using Real-time Feedback of Performance
08:16

Movement Retraining using Real-time Feedback of Performance

Published on: January 17, 2013

Moving faster while preserving accuracy.

O Missenard1, L Fernandez

  • 1Aix-Marseille University, UMR 6233 Human Movement Sciences Institute, 163 Avenue de Luminy, 13288 Marseille Cedex 09, France. olivier.missenard@yahoo.fr

Neuroscience
|September 28, 2011
PubMed
Summary
This summary is machine-generated.

Humans can move faster while maintaining accuracy by increasing muscle cocontraction. This strategy, though energetically costly, suggests a previously unrecognized trade-off between movement speed, energy, and accuracy.

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Area of Science:

  • Motor control
  • Biomechanics
  • Neuroscience

Background:

  • Achieving accurate movements despite neuromuscular variability is crucial for daily activities.
  • The speed-accuracy trade-off, where faster movements sacrifice accuracy, is a widely accepted principle.
  • Recent findings suggest muscle cocontraction can enhance movement accuracy, challenging existing models.

Purpose of the Study:

  • To investigate if humans can achieve faster and more accurate movements simultaneously.
  • To explore the role of muscle cocontraction in reconciling speed and accuracy.
  • To propose a new framework for understanding movement control strategies.

Main Methods:

  • Experimental manipulation of movement speed and accuracy requirements.
  • Measurement of joint torques and muscle activity during goal-directed movements.
  • Analysis of movement kinematics and muscle cocontraction levels.

Main Results:

  • Humans can indeed move faster while preserving accuracy by employing muscle cocontraction.
  • This cocontraction strategy is energetically expensive and not the default for fast, accurate movements.
  • A speed modulation strategy appears to be preferred over cocontraction for optimizing speed and accuracy.

Conclusions:

  • The traditional speed-accuracy trade-off may be an oversimplification.
  • Energy economy influences the choice of motor control strategies.
  • A novel speed-energy-accuracy trade-off likely governs goal-directed movements.