Related Experiment Video
Updated: May 29, 2026

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Cardiac rehabilitation outcomes: impact of comorbidities and age
Jennifer Listerman1, Vera Bittner, Bonnie K Sanderson
1University of Alabama at Birmingham, Birmingham, Alabama, USA.
Insights
Cardiac rehabilitation (CR) benefits all patients with coronary heart disease, irrespective of their medical comorbidity (CM) burden. Older patients with higher CM burden still gain significant improvements from CR, so it should not deter referrals.
Area of Science:
- Cardiology
- Rehabilitation Medicine
- Public Health
Background:
- Medical comorbidities (CM) are a known barrier to cardiac rehabilitation (CR) utilization.
- The impact of varying CM burden on CR outcomes in coronary heart disease (CHD) patients remains unclear.
Purpose of the Study:
- To determine if CHD patients with higher CM burden achieve similar benefits from CR compared to those with lower CM burden.
- To analyze the influence of age on the relationship between CM burden and CR outcomes.
Main Methods:
- Analysis of 794 CHD patients who completed CR between 1996 and 2008.
- Assessment of CM burden using a validated comorbidity index (CMI).
- Multivariable linear regression to compare changes in functional capacity (6-minute walk test), BMI, and SF-36 scores based on CMI and age groups.
Main Results:
- All patient subgroups, across all ages and CM burdens, showed improvements after CR.
- Younger patients (<56 years) with a CMI of 0 demonstrated greater improvements than those with higher CMI.
- In older age groups (≥56 years), the degree of improvement from CR was similar regardless of CM burden.
Conclusions:
- Cardiac rehabilitation (CR) is beneficial for all patients with coronary heart disease, irrespective of their medical comorbidity (CM) burden.
- High CM burden, particularly in older individuals, should not be a reason to withhold CR referrals.
- CR programs should be accessible to all CHD patients to maximize health benefits.
Purpose:
Medical comorbidities (CM) contribute to cardiac rehabilitation (CR) underutilization. Whether individuals with coronary heart disease and an increased CM burden achieve similar benefits from CR as those with a low CM burden is unknown.
Methods:
We analyzed 794 patients with coronary heart disease completing CR from 1/96 to 4/08. Medical CM burden was assessed using a comorbidity index (CMI) previously validated in a CR population. Distance achieved on a 6-minute walk test, body mass index, and the physical and mental component scores on the Medical Outcomes Short Form 36 were measured at baseline and at CR completion. We performed multivariable linear regression to compare changes in these parameters between individuals with a low CM burden (CMI = 0) and those with a moderate (CMI = 1-2) or high (CMI > 2) CM burden by age group (<56, 56-65, and >65 years of age).
Results:
Mean age was 61.6 ± 10.6 years, 29% were women, 31% nonwhite; 305 individuals had a CMI = 0, 305 had a CMI = 1 to 2, and 184 had a CMI > 2. All subgroups, regardless of age or CMI, demonstrated improvements with CR on virtually all parameters measured. Among individuals younger than 56 years, those with a CMI = 0 had greater improvements in these parameters after multivariable adjustment than those with a CMI of 1 to 2 or more than 2. In contrast, in older age groups, the degree of improvement was similar regardless of CMI.
Conclusion:
All patient groups, regardless of CM burden, benefited from CR. Medical CM burden, especially among older patients, should not discourage referral to CR.
Related Concept Videos
Cardiomyopathy V: Interprofessional Care
Pharmacodynamics in Geriatric Patients: Effects of Age
Cardiomyopathy II: Dilated Cardiomyopathy
Heart Failure III: Clinical Manifestations
Heart Failure VI: Adjunct Therapies
Heart Failure II: Pathophysiology
