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Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Vascular Spasm01:16

Vascular Spasm

The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last for...
Angina I: Introduction01:30

Angina I: Introduction

Definition and Symptoms: Angina (angina pectoris) is chest pain or discomfort caused by myocardial ischemia, which occurs when the heart muscle receives insufficient oxygen-rich blood. It typically manifests as pressing, squeezing, or crushing sensations in the chest and may radiate to the shoulders, arms, neck, jaw, or back.Primary Cause: In a healthy state, the coronary arteries can dilate (widen) to increase blood flow and meet the increased oxygen demand during physical activity or...
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...

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Related Experiment Video

Updated: May 29, 2026

Methods for Acute and Subacute Murine Hindlimb Ischemia
07:57

Methods for Acute and Subacute Murine Hindlimb Ischemia

Published on: June 21, 2016

Constriction "Band-Aid" syndrome causing digital ischaemia.

Jonathan Heather, Marcus Bisson

    The New Zealand Medical Journal
    |September 28, 2011
    PubMed
    Summary

    A simple Band-Aid on a child's finger wound caused severe tissue death, leading to digit amputation. This case highlights potential risks of common adhesive dressings.

    Area of Science:

    • Pediatric Medicine
    • Wound Care
    • Dermatology

    Background:

    • Standard wound care protocols often involve adhesive dressings for minor injuries.
    • Early recognition of complications from seemingly benign treatments is crucial in pediatric care.

    Observation:

    • A case report details a child who developed full-thickness necrosis after applying a standard adhesive dressing to a minor finger wound.
    • The necrosis progressed rapidly, necessitating surgical intervention.

    Findings:

    • The adhesive dressing, intended for protection, was implicated in the severe ischemic injury and subsequent tissue death.
    • Delayed diagnosis or inappropriate dressing application may have contributed to the adverse outcome.

    Implications:

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    High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
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    • This case underscores the importance of vigilant monitoring for adverse reactions to common medical supplies in children.
    • Healthcare providers should consider potential complications, even with minor wounds and simple dressings.
    • Further investigation into the mechanisms of adhesive-induced necrosis may be warranted.