Related Experiment Video
Updated: May 29, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Hyperreninemic hypertension following presumed abdominal trauma
Eduardo Pimenta1, Richard D Gordon, Nicholas Daunt
1Hypertension Unit, Princess Alexandra Hospital, 5th Floor, Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia. e.pimenta@uq.edu.au
Background:
An 18-year-old previously normotensive man was referred to a hypertension unit with blood pressure readings of 140-150/100-110 mmHg. Renal ultrasound had shown a right renal subcapsular fluid collection and an abdominal computed tomography scan had revealed a large cystic lesion surrounding the right kidney with a thick wall and irregular peripheral calcification consistent with a long-standing traumatic perinephric hematoma.
Investigations:
Physical examination, renal artery duplex ultrasonography, magnetic resonance imaging of the abdomen, isotopic renography with technetium-99m diethylenetriamine pentaacetic acid, and a renal venous renin ratio study.
Diagnosis:
Hyperreninemic hypertension as a result of presumed abdominal trauma.
Management:
Removal of the affected kidney.
Related Concept Videos
Hypertension II: Pathophysiology
Acute Kidney Injury II: Pathophysiology
Hormonal Regulation
Antihypertensive Drugs: Direct Renin Inhibitors
Hypertension and Regulation of Blood Pressure
Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors

