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Brugada pattern masking anterior myocardial infarction
1Cardiology Department, National University Health System, 1E Kent Ridge Road, Level 9, NUHS Tower Block, Singapore 119228. swee_chong_seow@nuhs.edu.sg
Brugada syndrome can mask ST elevation myocardial infarction (STEMI) on electrocardiograms (ECGs), complicating diagnosis. This case highlights the challenge of differentiating these critical cardiac conditions.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Brugada syndrome is an inherited cardiac channelopathy associated with ventricular arrhythmias.
- ST-elevation myocardial infarction (STEMI) is a critical condition requiring rapid diagnosis and intervention.
Observation:
- A middle-aged male smoker presented with chest pain and an initial ECG showing a Brugada Type 1 pattern.
- Subsequent ECGs and elevated cardiac enzymes indicated an evolving anterior STEMI.
- Coronary angiography revealed significant left anterior descending artery stenoses requiring emergent stenting.
Findings:
- The Brugada Type 1 pattern on the initial ECG obscured the diagnostic ECG changes of STEMI.
- This ECG pattern presented a diagnostic challenge, potentially delaying STEMI recognition.
Implications:
- Clinicians must consider the possibility of co-existing Brugada syndrome and STEMI in patients with atypical presentations.
- Awareness of how Brugada patterns can mask STEMI is crucial for timely diagnosis and management of acute coronary syndromes.
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