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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
[Secondary and tertiary prevention of urological tumors]
B J Schmitz-Dräger1, G Lümmen, E Bismarck
1Urologie, EuromedClinic, Europa-Allee 1, 90763, Fürth, Deutschland. bsd@euromed.de
Abstract:
The amount and quality of available data on secondary and tertiary prevention of urological tumors are to a large extent unsatisfactory. In the areas of nutrition and supplementary diet the consumption of tomatoes and especially tomato products could have a beneficial effect on the course of the disease for patients with prostate cancer, whereas there is evidence that the consumption of foodstuffs containing calcium (milk and milk products) and linolenic acid as well as a fat-rich diet accelerate tumor progression. Despite as yet unsatisfactory data, men with urothelial tumors or prostate cancer should abstain from smoking and undertake sports activities. For medicinal measures the administration of 5-alpha-reductase inhibitors and bone-promoting substances for patients with prostate cancer are under discussion. The effectiveness of the substances zoledronate and denosumab has been demonstrated in prospective randomized studies. The authors recommend that the scientifically neglected field of tertiary prevention of urological tumors should in future be included as a core factor of scientific investigations.
Insights
Dietary choices and lifestyle significantly impact urological tumor progression. Tomatoes may benefit prostate cancer patients, while dairy and fatty diets could accelerate it. Smoking cessation and exercise are recommended for better outcomes.
Area of Science:
- Urology
- Oncology
- Nutritional Science
Background:
- Data on secondary and tertiary prevention of urological tumors, particularly in nutrition and lifestyle, is insufficient.
- Existing research suggests specific dietary patterns and habits influence cancer progression.
Purpose of the Study:
- To review current knowledge on secondary and tertiary prevention strategies for urological tumors.
- To identify key nutritional and lifestyle factors affecting prostate cancer and urothelial tumors.
Main Methods:
- Literature review of studies on nutrition, diet, lifestyle, and medical interventions for urological tumor prevention.
- Analysis of evidence regarding the impact of specific foods (tomatoes, dairy, fats) and habits (smoking, exercise).
Main Results:
- Tomato consumption may benefit prostate cancer patients; dairy, linolenic acid, and high-fat diets may accelerate tumor progression.
- Smoking cessation and regular exercise are advised for men with urothelial tumors or prostate cancer.
- 5-alpha-reductase inhibitors and bone-promoting agents (zoledronate, denosumab) show effectiveness in prostate cancer management.
Conclusions:
- Tertiary prevention of urological tumors is scientifically neglected and requires further investigation.
- Personalized nutritional and lifestyle recommendations are crucial for managing urological tumors.
- Evidence-based medical interventions like bone-modifying agents should be considered in prostate cancer care.
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