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Implementation, process, and outcomes of nutrition best practices for infants <1500 g

Corrine Hanson1, Julie Sundermeier, Laura Dugick

  • 1School of Allied Health Professionals, University of Nebraska Medical Center, Omaha, NE 68198-4045, USA. ckhanson@unmc.edu

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
|September 28, 2011
PubMed

Insights

Optimizing nutrition for infants under 1500g birth weight significantly reduced extrauterine growth restriction. These changes improved growth outcomes and decreased chronic lung disease without adverse effects.

Area of Science:

  • Neonatalogy
  • Pediatric Nutrition
  • Growth Monitoring

Background:

  • Extrauterine growth restriction (EUGR) impacts infants with low birth weight (<1500g).
  • EUGR is linked to adverse neurodevelopmental outcomes.
  • Optimizing nutritional support is crucial for these vulnerable infants.

Purpose of the Study:

  • To evaluate the impact of enhanced nutrition administration on growth in infants weighing ≤1500g.
  • To assess changes in EUGR rates and other clinical outcomes following nutrition practice modifications.

Main Methods:

  • Retrospective chart review comparing infants before and after nutrition practice changes.
  • Key changes included early aggressive parenteral nutrition, early enteral feedings, and fortified breast milk.
  • Analysis included demographics, growth parameters, feeding outcomes, and discharge status, with subgroup analysis for infants ≤1000g and 1000-1500g.

Main Results:

  • EUGR at discharge decreased from 57% to 28% (P=.01) post-intervention.
  • Weight percentile ranking at 36 weeks' GA improved significantly for infants 1001-1500g (13th to 27th percentile).
  • Chronic lung disease incidence decreased significantly (P=.02); necrotizing enterocolitis and blood urea nitrogen levels did not increase.

Conclusions:

  • Defined nutritional practice changes significantly improved growth outcomes in infants ≤1500g.
  • The implemented strategies enhanced growth without increasing adverse clinical outcomes.
  • This study supports the benefits of optimized nutrition for improving growth in high-risk neonates.
Abstract

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