Related Experiment Video
Updated: May 29, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Totally transvaginal resection of the descending colon in an experimental model
Francisco Alba Mesa1, Antonio Amaya Cortijo, Jose Manuel Romero Fernandez
1Consorcio Sanitario Publico del Aljarafe, Hospital San Juan de Dios, Bormujos (Sevilla), Spain.
Background:
Natural orifice translumenal endoscopic surgery (NOTES), although in its embryonic phase, is currently experiencing important developments. The technique has been successfully applied for cholecystectomies and appendectomies. However, several doubts exist as to the technical limitations and feasibility of NOTES in other clinical settings.
Methods:
The authors have performed totally transvaginal colon resections in a sheep model. Although completion of the surgery was possible through the transvaginal route, the addition of a transumbilical laparoscope was used as an added safety measure.
Results:
Totally transvaginal resection of the sigmoid colon was performed for two sheep with no intra- or postoperative complications.
Conclusion:
Totally transvaginal resection of the colon (pure NOTES) is feasible in a sheep model.

