Related Experiment Video
Updated: May 29, 2026

Zebrafish Brain Ventricle Injection
Published on: April 6, 2009
Patterning and development of the atrioventricular canal in zebrafish
David S Peal1, Stacey N Lynch, David J Milan
1Cardiovascular Research Center and Cardiac Arrhythmia Service, Harvard Medical School, Massachusetts General Hospital, 149 13th Street, Charlestown, Boston, MA 02129, USA.
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Proper atrioventricular canal (AVC) patterning and subsequent valvulogenesis is a complex process, and defects can result in disease or early death. The zebrafish Danio rerio has become a useful model system for studying AVC development, and much progress has been made in dissecting out the critical steps. Here, we review the recent advances in the field and highlight the cellular and molecular changes observed during zebrafish AVC development.

