Related Experiment Video
Updated: May 29, 2026

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
Antiretroviral adherence and the nature of HIV-associated verbal memory impairment
Matthew J Wright1, Ellen Woo, Jessica Foley
1Psychology Division, Department of Psychiatry, Harbor-UCLA Medical Center, Torrance, CA, USA. mwright@labiomed.org
Abstract:
The authors investigated the relationship between antiretroviral adherence and HIV-associated verbal memory impairment. HIV-positive participants demonstrated poorer verbal memory than HIV-negative participants. Both good (≥90%) and poor (<90%) adherers displayed encoding deficits as compared with controls, but only poor adherers exhibited retrieval deficits. Encoding deficits primarily accounted for reduced delayed recall in good adherers, but both encoding and retrieval deficits accounted for reduced delayed recall in poor adherers. The retrieval difference between the adherence groups might be explained by a neuroprotective effect of good antiretroviral adherence or preexisting HIV-related retrieval deficits that result in poorer adherence.
Related Concept Videos
Retrovirus Life Cycles
Size and Structure of Viral Genomes
Inhibitors of Virion Maturation and Assembly
Amebiasis
Amnesia
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
Higher Mental Functions of Brain: Learning and Memory

