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Update on diabetic nephropathy in NIDDM.

W H Dere1, G C Groggel

  • 1Department of Internal Medicine, Indiana University School of Medicine.

Geriatrics
|July 1, 1990
PubMed
Summary

Diabetic nephropathy affects many older adults, with non-insulin-dependent diabetes mellitus (NIDDM) being a leading cause of chronic kidney disease. This review covers NIDDM-related kidney disease epidemiology, causes, and management in the elderly.

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Area of Science:

  • Nephrology
  • Endocrinology
  • Geriatrics

Background:

  • Diabetic nephropathy is a significant complication in the elderly.
  • Non-insulin-dependent diabetes mellitus (NIDDM) is prevalent in geriatric patients requiring dialysis.
  • NIDDM patients with chronic renal insufficiency significantly outnumber those with insulin-dependent diabetes mellitus.

Purpose of the Study:

  • To review the epidemiology of diabetic nephropathy in the geriatric population.
  • To discuss the pathogenesis of diabetic nephropathy.
  • To highlight clinical evaluation and treatment considerations for NIDDM patients.

Main Methods:

  • Literature review of epidemiology and pathogenesis.
  • Discussion of clinical evaluation strategies.
  • Outline of treatment considerations.

Main Results:

  • NIDDM is a major driver of chronic kidney disease in the elderly.
  • Understanding epidemiology and pathogenesis is crucial for management.
  • Specific clinical considerations are necessary for NIDDM patients.

Conclusions:

  • Diabetic nephropathy poses a substantial burden on geriatric healthcare.
  • Effective management requires a thorough understanding of NIDDM's impact on renal health.
  • This review provides a foundation for addressing this growing clinical challenge.

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