Related Experiment Video
Updated: May 29, 2026
Assessment and Communication for People with Disorders of Consciousness
Published on: August 1, 2017
A learning assessment procedure as a test supplement for monitoring progress with two post-coma persons with a
Giulio Lancioni1, Nirbhay Singh, Mark O'Reilly
1Department of Psychology, University of Bari, Bari, Italy. g.lancioni@psico.uniba.it
Objective:
Evaluating a learning assessment procedure for monitoring progress with two post-coma adults with a diagnosis of vegetative state.
Method:
ABABCBCB and ABABCB designs were used for the two participants, with A representing baseline, B intervention and C control conditions. Participants' activation of an optic microswitch by eyelid closure produced stimulation during B phases.
Results:
One participant increased responding during B phases and decreased it during the C condition, suggesting a non-reflective minimal level of consciousness. She showed P300 and mismatch negativity responses and scored at the vegetative level on the Coma Recovery Scale-Revised (CRS-R). The other participant increased responding during the initial B phases without decline during the first (viable) part of the C condition, suggesting a pre-conscious level. He showed indistinct P300 and mismatch negativity responses and vegetative-level scores on the CRS-R.
Conclusion:
Learning data seemed reconcilable with neurophysiological measures and more positive than CRS-R scores.
