Related Experiment Video

Updated: May 29, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
08:03

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model

Published on: November 4, 2025

Failure to thrive in infants with complicated facial hemangiomas

Meghan W Thomas1, Craig N Burkhart, Sapna P Vaghani

  • 1Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina 27514, USA. mwthomas@unch.unc.edu

Pediatric Dermatology
|September 29, 2011
PubMed

Insights

Infants with facial hemangiomas may experience feeding difficulties and failure to thrive due to oral sensory impairments. Early intervention by speech or occupational therapists is recommended for at-risk infants.

Area of Science:

  • Pediatric Medicine
  • Developmental Pediatrics
  • Otolaryngology

Background:

  • Facial hemangiomas of infancy are common vascular tumors.
  • Feeding difficulties and failure to thrive can impact infant development.
  • Oral sensory processing plays a crucial role in infant feeding.

Observation:

  • Children with facial hemangiomas sometimes present with feeding issues and failure to thrive.
  • A review of four cases examined oral sensory and feeding experiences.
  • Parental surveys and medical records were utilized for data collection.

Findings:

  • All infants with feeding irregularities showed some oral sensory impairment.
  • Early oral sensory intervention was required for these infants.
  • There were varied reports on the difficulty and delay in oral feeding development.

Implications:

  • Infants with complex facial hemangiomas, especially with perioral or airway involvement, are at higher risk.
  • Close monitoring for failure to thrive is crucial in these infants.
  • Early evaluation by speech or occupational therapists is recommended for optimal outcomes.

More Related Videos

Facial Transplants in Xenopus laevis Embryos09:08

Facial Transplants in Xenopus laevis Embryos

Published on: March 26, 2014

Quantification of Orofacial Phenotypes in Xenopus09:26

Quantification of Orofacial Phenotypes in Xenopus

Published on: November 6, 2014

Related Concept Videos

Prosopagnosia01:24

Prosopagnosia

Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl hydroxylase and factor...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Development of Blood Vessels01:07

Development of Blood Vessels

The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...