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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Related Experiment Video

Updated: May 29, 2026

An In Vitro Approach to Photodynamic Therapy
04:53

An In Vitro Approach to Photodynamic Therapy

Published on: August 17, 2018

Photo(chemo)therapy for vitiligo.

Alessia Pacifico1, Giovanni Leone

  • 1Photodermatology Unit, San Gallicano Dermatological Institute, Roma, Italy.

Photodermatology, Photoimmunology & Photomedicine
|September 29, 2011
PubMed
Summary
This summary is machine-generated.

Vitiligo treatment options are diverse, including phototherapy, steroids, and surgery. Narrow-band ultraviolet B (NB UVB) is a gold standard, while targeted phototherapy with 308 nm excimer sources shows promise for localized vitiligo.

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Area of Science:

  • Dermatology
  • Photomedicine

Background:

  • Vitiligo is a prevalent skin condition involving melanin pigment loss, with unclear pathogenesis.
  • Current treatments for vitiligo encompass a range of modalities, including phototherapy, corticosteroids, and surgical interventions.

Purpose of the Study:

  • To review and discuss current and emerging phototherapy options for vitiligo treatment.
  • To highlight the efficacy of narrow-band ultraviolet B (NB UVB) and targeted phototherapy for vitiligo.

Main Methods:

  • Review of existing literature on vitiligo treatment modalities.
  • Focus on phototherapy, including narrow-band ultraviolet B (NB UVB) and excimer laser/light therapies.

Main Results:

  • Narrow-band ultraviolet B (NB UVB) is considered the gold standard for diffuse vitiligo.
  • 308 nm excimer laser and light (targeted phototherapy) are effective for localized vitiligo.

Conclusions:

  • Phototherapy, particularly NB UVB and targeted 308 nm excimer treatments, are key therapeutic strategies for vitiligo.
  • Targeted phototherapy may be the preferred option for localized vitiligo cases.