Related Experiment Video
Updated: May 29, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
Caesarean section: impact on mother and child
T Boutsikou1, A Malamitsi-Puchner
1Neonatal Division, Second Department of Obstetrics and Gynecology, University of Athens, Athens, Greece.
Repeat cesarean sections (CS) carry risks for mothers and babies, including complications like uterine rupture and neonatal issues. Early elective CS before 39 weeks gestation increases infant health problems and intensive care admissions.
Area of Science:
- Obstetrics and Gynecology
- Neonatal Health
- Perinatal Medicine
Background:
- Repeat cesarean sections (CS) are associated with significant maternal and fetal risks.
- Elective CS before 39 weeks gestation is linked to increased neonatal complications.
- Cesarean birth influences neonatal gut microbiome, potentially affecting long-term health.
Purpose of the Study:
- To review the maternal and neonatal complications associated with repeat cesarean sections.
- To highlight risks of early elective cesarean delivery.
- To discuss the impact of cesarean birth on infant health outcomes.
Main Methods:
- Literature review of studies on cesarean section outcomes.
- Analysis of maternal morbidity and mortality associated with repeat CS.
- Examination of neonatal complications following elective and repeat CS.
Main Results:
- Repeat CS increases risks of uterine rupture, placenta previa/increta, and stillbirth.
- Early elective CS (before 39 weeks) correlates with respiratory issues, hypoglycemia, sepsis, and NICU admissions.
- CS-born neonates exhibit altered gut colonization, linked to allergies, asthma, and potentially type 1 diabetes and childhood malignancies.
Conclusions:
- Maternal and neonatal risks must be considered when deciding on primary cesarean sections.
- Timing of elective CS impacts neonatal outcomes, with risks increasing before 39 weeks.
- Long-term health implications for neonates born via CS warrant further investigation.
Related Concept Videos
Development of the Oral Microbiota
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Development of Human Microbiota
Teratogenicity
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...

