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Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
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Silicone breast implants--is there cause for concern?
B W Van Natta1, J B Thurston, T S Moore
1Indianapolis Plastic Surgeons, IN 46260.
Abstract:
Recent controversy has arisen regarding the potential carcinogenesis of medical silicone-gel as used in breast implants. A review of the pertinent literature shows that although rodents do demonstrate the development of sarcomas to any inert material, including silicone-gel, the phenomenon is species specific. No clinical evidence of carcinogenesis in humans has been noted in more than 25 years of use. We conclude that silicone-gel breast implants are safe.
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