Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

What is Genetic Engineering?

What is Genetic Engineering?

Ethical Issues

Ethical Issues

Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:

Human Genetics

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...

Ethics and Bioethics

Ethics and Bioethics

Ethics is a philosophical study of moral actions. Ethics attempts to determine what is valuable for individuals and society. It examines the rational justification of moral judgments and analyzes what is morally just, fair, and right. Bioethics is a sub-discipline of applied ethics that analyzes the philosophical, social, and legal issues in life sciences and medicine. Ethical theories serve as a foundation for decision-making and represent the viewpoints from which people seek direction. They...

Genetic Screens

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...

CRISPR

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

How feasible is nutrition intervention research in eating disorders? Lessons learnt from a pilot parallel randomised controlled trial of tyrosine supplementation in adolescents with anorexia nervosa.

Journal of eating disorders·2024

Same author

Effectiveness of early hematopoietic stem cell transplantation in preventing neurocognitive decline in aspartylglucosaminuria: A case series.

JIMD reports·2021

Same author

Progressing our understanding of the impacts of nutrition on the brain and behaviour in anorexia nervosa: a tyrosine case study example.

Journal of eating disorders·2021

Same author

Are We Ready for Fragile X Newborn Screening Testing?-Lessons Learnt from a Feasibility Study.

International journal of neonatal screening·2020

Same author

Newborn Screening for Lysosomal Disease: Mission Creep and a Taste of Things to Come?

International journal of neonatal screening·2020

Same author

Association of elevated neonatal thyroid-stimulating hormone levels with school performance and stimulant prescription for attention deficit hyperactivity disorder in childhood.

European journal of pediatrics·2020

Search research articles

Related Experiment Video

Updated: May 29, 2026

Working with Human Tissues for Translational Cancer Research

Working with Human Tissues for Translational Cancer Research

Published on: November 26, 2015

Ethical issues in genetics.

Bridget Wilcken¹

¹Biochemical Genetics and Newborn Screening Departments, The Children's Hospital at Westmead, Sydney, New South Wales, Australia. bridgetw@chw.edu.au

Journal of Paediatrics and Child Health

|September 29, 2011

Summary

Genetic testing for inherited disorders presents ethical challenges, including family privacy, predictive risk interpretation, and direct-to-consumer test concerns. Advances in genetic technologies necessitate careful ethical consideration in clinical genetics practice.

More Related Videos

FISH for Pre-implantation Genetic Diagnosis

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

Related Experiment Videos

Last Updated: May 29, 2026

Working with Human Tissues for Translational Cancer Research

Working with Human Tissues for Translational Cancer Research

Published on: November 26, 2015

FISH for Pre-implantation Genetic Diagnosis

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

Area of Science:

Clinical genetics
Bioethics
Genomic medicine

Background:

Genetic disorders stem from gene and chromosome abnormalities, impacting family dynamics and privacy.
Genetic testing offers diagnostic and predictive insights but raises complex ethical questions.
Emerging technologies like whole genome sequencing and direct-to-consumer testing amplify these ethical concerns.

Purpose of the Study:

To explore the multifaceted ethical implications of genetic testing in clinical practice.
To address concerns related to family confidentiality, predictive testing, and informed consent.
To highlight the ethical considerations arising from new reproductive technologies and direct-to-consumer genetic services.

Main Methods:

Review of current ethical guidelines and literature in clinical genetics.
Analysis of case studies involving genetic testing and family implications.
Discussion of emerging technologies and their ethical impact.

Main Results:

Genetic testing necessitates robust pre-test counseling and consideration of third-party disclosure.
Interpretation of predictive genetic information, especially for future risks, requires careful management due to imprecision.
Direct-to-consumer genetic testing and advancements in reproductive medicine introduce novel ethical dilemmas.

Conclusions:

Ethical considerations are paramount in clinical genetics due to the personal and familial nature of genetic information.
The increasing accessibility of genetic testing technologies demands ongoing ethical scrutiny and policy development.
Ensuring responsible innovation in genetic technologies requires a proactive approach to ethical challenges.