Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 29, 2026

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

High-throughput rheology in a microfluidic device.

Kelly M Schultz¹, Eric M Furst

¹Department of Chemical Engineering and Center for Molecular and Engineering Thermodynamics, University of Delaware, Newark, Delaware 19716, USA.

|September 29, 2011

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Magnetostatic energies in crystals of paramagnetic particles.

Physical review. E·2026

Same author

A technique to create hydrogels with tethered concentration gradients of molecules <i>in vitro</i>.

Soft matter·2026

Same author

Design and Characterization of Thioester Networks with Adaptable and Enzymatically Degradable Cross-Links.

Macromolecules·2025

Same author

Quantitative Imaging of Colloidal Structures.

Langmuir : the ACS journal of surfaces and colloids·2025

Same author

Sequential Growth of Quantized Peptide Brushes on Colloidal Gold.

Langmuir : the ACS journal of surfaces and colloids·2025

Same author

Cell-Material Interactions in Covalent Adaptable Thioester Hydrogels.

ACS biomaterials science & engineering·2024

This study introduces high-throughput rheological measurements using microfluidics. This method efficiently characterizes material properties with minimal sample volume, ideal for scarce or expensive substances.

Area of Science:

Fluid dynamics
Materials science
Biophysics

Background:

Traditional rheological measurements can be time-consuming and require significant sample volumes.
Characterizing the rheological properties of scarce or expensive materials presents a significant challenge.

Purpose of the Study:

To develop a high-throughput method for rheological measurements using microfluidics.
To enable continuous variation of sample composition for comprehensive material characterization.
To minimize sample preparation time and material consumption.

Main Methods:

Generating sample droplets in an immiscible spacer fluid using a microfluidic T-junction.
Performing multiple particle tracking microrheology within individual droplets.

More Related Videos

Development of a Microfluidics-Based Approach for Investigating Microtubule Polymer Mechanics

Development of a Microfluidics-Based Approach for Investigating Microtubule Polymer Mechanics

Published on: May 30, 2025

A Microfluidic Device for Studying Multiple Distinct Strains

A Microfluidic Device for Studying Multiple Distinct Strains

Published on: November 9, 2012

Related Experiment Videos

Last Updated: May 29, 2026

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

Development of a Microfluidics-Based Approach for Investigating Microtubule Polymer Mechanics

Development of a Microfluidics-Based Approach for Investigating Microtubule Polymer Mechanics

Published on: May 30, 2025

A Microfluidic Device for Studying Multiple Distinct Strains

A Microfluidic Device for Studying Multiple Distinct Strains

Published on: November 9, 2012

Continuously varying sample compositions across a wide range.

Main Results:

Demonstrated successful high-throughput rheological measurements in a microfluidic device.
Validated the method by measuring the viscosity of glycerine and heparin solutions.
Optimized critical parameters including droplet size and flow rates.

Conclusions:

The integration of microfluidics and microrheology offers a powerful approach for rapid material characterization.
This technique significantly reduces sample volume and preparation time.
It is particularly advantageous for analyzing rare or costly materials.