[Experimental study with Doppler ultrasound in partial chronic obstructive uropathy]

Area of Science:

• Veterinary Medicine
• Medical Imaging
• Nephrology

Background:

• Assessing hemodynamic parameters of the renal artery using Doppler Ultrasound.
• Evaluating Renal Resistive Index (RI), Peak Systolic Velocity (PSV), End-Diastolic Velocity (EDV), and Blood Flow (FR).
• Focusing on diagnosis and monitoring of postsurgical partial chronic obstructive uropathy.

Purpose of the Study:

• To assess Doppler Ultrasound parameters for diagnosing and monitoring obstructive uropathy.
• To determine the efficacy of specific hemodynamic parameters, particularly EDV, in obstructive uropathy.
• To evaluate the utility of these parameters in postsurgical and endourological follow-up.

Main Methods:

• Utilized duplex-Doppler evaluation in 50 pigs to measure renal hemodynamic parameters.
• Created a partial right ureteral obstruction model and assessed parameters in three phases: baseline, diagnosis/treatment, and 6-month follow-up.
• Employed fluoroscopic examinations including cystography, excretory urography, and retrograde ureteropyelography for diagnosis.

Main Results:

• End-diastolic velocity (EDV) and its ratio demonstrated high sensitivity and specificity for diagnosing obstructive uropathy.
• Postoperative monitoring indicated that RI and EDV returned to baseline levels after treatment.
• The change in EDV (ΔEDV) and its ratio proved to be the most effective diagnostic marker.

Conclusions:

• The ΔEDV and its ratio are highly effective for diagnosing chronic partial obstructive uropathy, though not a replacement for conventional methods.
• Doppler Ultrasound parameters, especially EDV, are valuable complementary tools for monitoring patients after endourological treatment of obstructive uropathy.
• Hemodynamic assessment via Doppler Ultrasound offers crucial insights into renal function and recovery in obstructive uropathy cases.