Related Experiment Videos
Value of random US-guided transrectal prostate biopsy.
1Department of Radiology, University of Toronto, Toronto General Hospital, Ont., Canada.
Radiology
|August 1, 1990
Summary
Random prostatic biopsy offers a distinct, clinically relevant yield in diagnosing prostate cancer, even when initial nodules appear suspicious. This method aids in management decisions for some patients.
Area of Science:
- Urology
- Oncology
- Diagnostic Imaging
Background:
- Prostate nodules suspicious for malignancy are often biopsied.
- The diagnostic contribution of random biopsy alongside targeted biopsy is not fully established.
Purpose of the Study:
- To evaluate the contribution of random biopsy to the diagnosis, staging, and management of prostate cancer in men with suspicious prostatic nodules.
Main Methods:
- 164 men underwent ultrasound-guided transrectal biopsy of suspicious prostatic nodules and random biopsy of normal-appearing areas.
- Diagnosis, clinical staging, and management alterations were assessed.
Main Results:
- Prostate cancer was diagnosed in 43.3% of patients.
- Random biopsy alone diagnosed cancer in 7% of cases, contributing to management changes in 5 patients.
- Clinical staging was not significantly altered by random biopsy.
Conclusions:
- Random prostatic biopsy provides a small but clinically relevant additional yield in diagnosing prostate cancer.
- The procedure is considered useful in evaluating patients with suspicious prostatic nodules.