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Updated: May 29, 2026

Development of a Neonatal Rat Model for Brachial Plexus Birth Injury
Published on: March 27, 2026
Shoulder sequelae of neonatal brachial plexus injuries: orthopedic assessment and management
Abhishek Julka1, Kelly L Vander Have
1Department of Orthopaedic Surgery, University of Michigan Hospitals, Ann Arbor, MI 48109, USA. klvander@umich.edu
Insights
Neonatal brachial plexus palsy (NBPP) can cause shoulder problems due to muscle imbalance, potentially leading to long-term disability. Early orthopedic evaluation and management are crucial for recognizing and treating these shoulder sequelae effectively.
Area of Science:
- Pediatric Orthopedics
- Neonatal Care
- Neurology
Background:
- Brachial plexus birth palsy affects 1-4/1000 live births, often resulting in permanent neurologic deficits.
- Muscle imbalance from brachial plexus birth palsy leads to shoulder pathology, including soft tissue contractures and glenohumeral joint changes.
- Internal rotation contractures are common, causing significant disability in affected children.
Purpose of the Study:
- To review the orthopedic evaluation and management of neonatal brachial plexus palsy (NBPP).
- To emphasize the importance of early recognition and prompt referral for NBPP.
- To guide clinicians in managing shoulder sequelae associated with NBPP.
Main Methods:
- Review of existing literature on neonatal brachial plexus palsy and its orthopedic management.
- Analysis of clinical presentation, diagnostic methods, and treatment strategies.
- Emphasis on physical examination, imaging, and family-centered goal assessment.
Main Results:
- Spontaneous recovery occurs in most cases, but some infants develop permanent neurologic deficits.
- Shoulder pathology, including contractures and joint changes, can progress and limit function.
- Surgical intervention is considered for functionally limiting contractures, joint changes, or instability.
Conclusions:
- Early recognition and appropriate management of shoulder sequelae in NBPP are essential.
- A comprehensive approach involving physical examination, imaging, and family expectations is critical.
- Prompt referral and orthopedic intervention can improve shoulder function and prevent long-term disability.
Abstract:
Brachial plexus birth palsy occurs at a rate of 1/1000-4/1000 live births despite advances in prenatal and obstetric care. The majority of children recover spontaneously, however some are left with permanent neurologic deficit. Shoulder pathology results from muscle imbalance created by pairing of weak or paralyzed muscles with unaffected muscle groups around the shoulder. This imbalance results in soft tissue contracture and can cause progressive glenohumeral joint morphological changes. Contractures of internal rotation are most common and may be a source of disability for the child. Treatment of the infant with brachial plexus palsy is initially centered around therapy and prevention of contracture. Surgical intervention can improve global shoulder function, and is reserved for patients who develop functionally limiting contractures, glenohumeral joint morphological changes, or findings of instability. A thorough physical examination, appropriate imaging, and assessment of the goals and expectations of the family are warranted prior to proceeding with any treatment course. The progressive and functionally limiting course of the shoulder sequelae in brachial plexus palsy emphasizes the need for early recognition and appropriate management. The purpose of this manuscript is to review orthopedic evaluation and management of neonatal brachial plexus palsy (NBPP) to promote early recognition and prompt referral.
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