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Related Experiment Video

Updated: May 29, 2026

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

Aging and late-life depression.

Zheng Wu¹, Christoph M Schimmele, Neena L Chappell

¹University of Victoria, Victoria, British Columbia, Canada. zhengwu@uvic.ca

Journal of Aging and Health

|September 30, 2011

Summary

Late-life depression shows a complex relationship with aging. While depressive symptoms linearly increase with age, major depression follows a U-shaped pattern, influenced by medical factors.

Area of Science:

Gerontology
Psychiatry
Epidemiology

Background:

Late-life depression is a significant public health concern.
Understanding the relationship between aging and depression is crucial for effective interventions.

Purpose of the Study:

To investigate the association between age and depression in individuals aged 65 and older.
To analyze the trajectories of depressive symptoms and major depression in later life.

Main Methods:

Utilized three waves of longitudinal data (1991, 1996, 2001) from a Canadian sample of individuals aged 65+.
Employed generalized linear mixed-model techniques to estimate depression trajectories.
Included both community-dwelling and institutionalized populations.

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A New Method for Inducing a Depression-Like Behavior in Rats

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Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

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A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Main Results:

A linear increase in depressive symptoms was observed after age 65, primarily linked to medical comorbidity, not aging itself.
A significant U-shaped relationship between age and major depression was identified after adjusting for covariates.
Findings suggest distinct risk factors for depression in late life compared to earlier life stages.

Conclusions:

The association between age and late-life depression is multifaceted, varying with measurement methods.
The "fourth age" (very old age) is characterized by increased psychiatric morbidity.
Late-life depression development is influenced by unique risk factors, differing from those in younger populations.