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Association of intracranial meningioma with arteriovenous malformation
1Department of Neurology, State University of New York/Buffalo School of Medicine.
Abstract:
Simultaneous occurrence of a cerebral arteriovenous malformation and a primary brain tumor is rare. A case of a left occipital meningioma and a right parietotemporal arteriovenous malformation is reported. Clinical, radiological, and postmortem findings are described. Thirty previous reports of arteriovenous malformations associated with primary brain tumors are reviewed. In 18 cases the two lesions were intermixed or in close proximity. This spatial relationship between the lesions suggests more than a coincidental association. Several hypotheses are proposed to explain common causal connections.
Insights
Simultaneous brain arteriovenous malformations (AVMs) and primary brain tumors are rare. This study reports a case and reviews 30 others, suggesting a potential non-coincidental association between these vascular and neoplastic lesions.
Area of Science:
- Neurology
- Neurosurgery
- Radiology
Background:
- Cerebral arteriovenous malformations (AVMs) and primary brain tumors are distinct neurological conditions.
- The simultaneous occurrence of both AVMs and brain tumors is exceptionally rare in clinical practice.
Observation:
- A unique case involving a left occipital meningioma and a right parietotemporal AVM is presented.
- Detailed clinical, radiological, and postmortem data were collected for this specific case.
- A comprehensive review of 30 prior reports on AVMs associated with primary brain tumors was conducted.
Findings:
- In a significant proportion of reviewed cases (18 out of 30), the AVM and brain tumor were found to be intermixed or in close anatomical proximity.
- This close spatial relationship challenges the notion of a purely coincidental association between these two pathologies.
Implications:
- The observed spatial relationship suggests potential shared etiological factors or developmental links between cerebral AVMs and primary brain tumors.
- Further research is warranted to explore these common causal connections and their underlying mechanisms.
- Understanding this association may refine diagnostic and treatment strategies for patients presenting with either condition.