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An enhanced DNA fingerprinting service to investigate potential Clostridium difficile infection case clusters sharing
Warren N Fawley1, Mark H Wilcox,
1Department of Microbiology, The General Infirmary, Old Medical School, Leeds LS1 3EX, United Kingdom.
Abstract:
Of 53 potential Clostridium difficile infection (CDI) case clusters/outbreaks, affecting 2 to 41 patients in 27 institutions, 19% comprised unrelated isolates and 34% had highly related and distinct isolates as shown by multilocus variable-number tandem-repeat analysis, despite sharing a common ribotype. These findings emphasize the value of enhanced fingerprinting to confirm or refute suspected CDI case clusters.
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