[Thromboelastography as a method for preoperative assessment of hemostasis state in neurosurgical patients on long

Insights

Thromboelastography (TEG) effectively assesses bleeding risk in neurosurgical patients on aspirin. Hypocoagulation identified by TEG correlates with higher postoperative hemorrhage, necessitating surgery postponement.

Area of Science:

  • Neurosurgery
  • Hematology
  • Anesthesiology

Context:

  • Aspirin is commonly used for long-term therapy, posing risks for surgical patients.
  • Assessing hemostasis in patients on aspirin therapy is crucial for surgical safety.
  • Traditional tests may not fully capture the hemostatic status in these patients.

Purpose:

  • To evaluate the utility of thromboelastography (TEG) in assessing hemostasis in neurosurgical patients on long-term aspirin therapy.
  • To correlate TEG findings with the incidence of postoperative hemorrhagic complications.
  • To guide clinical decisions regarding aspirin therapy interruption and surgical timing.

Summary:

  • 169 patients on long-term aspirin therapy undergoing neurosurgery were assessed using routine tests and TEG.
  • Patients were categorized into normo-, hypo-, and hypercoagulation groups based on TEG results.
  • Aspirin was interrupted in normo- and hypercoagulation groups with no surgery postponement; in hypocoagulation, surgery was postponed 3-5 days post-interruption until TEG normalized.
  • The hypocoagulation group exhibited the highest rate of postoperative hemorrhage complications.
  • TEG proved to be a prompt and effective tool for assessing hemostasis in this patient cohort.

Impact:

  • Thromboelastography provides a rapid and effective method for evaluating hemostasis in neurosurgical patients on aspirin.
  • Identifying hypocoagulation via TEG allows for timely intervention, potentially reducing hemorrhagic complications.
  • This study supports the integration of TEG into the perioperative management of patients on antithrombotic therapy.