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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Herpes01:28

Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Disorders of Leukocytes01:27

Disorders of Leukocytes

Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
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Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Related Experiment Video

Updated: May 29, 2026

Necropsy-based Wild Fish Health Assessment
07:57

Necropsy-based Wild Fish Health Assessment

Published on: September 11, 2018

[Surprising white lesions].

J W Nolte1, I van der Waal

  • 1Afdeling Mondziekten, Kaak- en Aangezichtschirurgie/Orale pathologie van het VU Medisch Centrum in Amsterdam/Academisch, Centrum Tandheelkunde Amsterdam (ACTA). j.nolte@vumc.nl

Nederlands Tijdschrift Voor Tandheelkunde
|October 1, 2011
PubMed
Summary

Syphilis, though rare, can present as white oral lesions. Prompt diagnosis through advanced biopsy techniques is crucial for effective treatment with penicillin, leading to lesion resolution.

Area of Science:

  • Oral Medicine
  • Infectious Diseases
  • Pathology

Background:

  • Syphilis is a complex sexually transmitted infection.
  • Oral manifestations of syphilis can be diverse and sometimes subtle.
  • Delayed diagnosis can lead to significant health complications.

Observation:

  • A 46-year-old male presented with persistent white oral lesions.
  • Initial biopsy and symptomatic treatment (mouth rinse) were inconclusive and ineffective.
  • A second biopsy with advanced pathological testing was performed.

Findings:

  • The advanced biopsy successfully diagnosed syphilis as the cause of the oral lesions.
  • Treatment with benzylpenicillin resulted in the complete disappearance of the lesions.

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Necropsy-based Wild Fish Health Assessment
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Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
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Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

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Implications:

  • This case highlights the importance of considering syphilis in the differential diagnosis of unexplained oral lesions.
  • Advanced diagnostic methods are vital for identifying rare or atypical presentations of infectious diseases.
  • Early and accurate diagnosis of syphilis is essential for successful treatment and preventing transmission.