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Related Concept Videos

Polytene Chromosomes02:04

Polytene Chromosomes

Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also regularly...
Polytene Chromosomes02:04

Polytene Chromosomes

Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also regularly...
Polygenic Traits01:18

Polygenic Traits

When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
Polygenic Traits01:18

Polygenic Traits

When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
Epistasis Analysis01:09

Epistasis Analysis

Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...

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Related Experiment Video

Updated: May 29, 2026

A Modified Technique for Inducing Polycystic Ovary Syndrome in Mice
04:49

A Modified Technique for Inducing Polycystic Ovary Syndrome in Mice

Published on: July 5, 2024

A polyorchid dog.

T M Tamminen1, M R Leinonen, H Käck

  • 1Department of Reproduction Animals, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland. tuire.tamminen@helsinki.fi

Reproduction in Domestic Animals = Zuchthygiene
|October 1, 2011
PubMed
Summary

Polyorchidism, a rare condition, was diagnosed in an Irish Setter with three testes. Surgical removal of two testes did not fully resolve testosterone production, indicating a complex anatomical anomaly.

Area of Science:

  • Veterinary Medicine
  • Reproductive Biology
  • Canine Health

Background:

  • Polyorchidism, the presence of supernumerary testes, is a rare congenital anomaly in domestic animals.
  • Early detection and surgical intervention are crucial for managing reproductive abnormalities in dogs.

Observation:

  • A one-year-old Irish Setter presented with polyorchidism, having one scrotal and two cryptorchid testes.
  • Initial castration and removal of a scrotal and an inguinal cryptorchid testis were performed.
  • Persistent testosterone production prompted further investigation.

Findings:

  • A third, abdominal cryptorchid testis was identified cranially to the bladder on the right side.
  • This testis possessed a robust cranial suspensory ligament and an elongated epididymal tail.

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A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
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A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

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Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy
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Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy

Published on: May 24, 2016

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Last Updated: May 29, 2026

A Modified Technique for Inducing Polycystic Ovary Syndrome in Mice
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A Modified Technique for Inducing Polycystic Ovary Syndrome in Mice

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A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
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A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

Published on: October 2, 2018

Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy
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Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy

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  • The ductus deferens of the third testis followed the gubernaculum to the inguinal region, suggesting a shared duct with the previously removed caudal right testis.
  • Implications:

    • This case highlights the importance of thorough diagnostic evaluation in cases of persistent hormonal activity post-surgery.
    • The anatomical findings suggest a potential shared ductus deferens between two right-sided cryptorchid testes, a rare occurrence.
    • Understanding such complex anatomical variations is vital for successful surgical outcomes and managing reproductive health in canines.